Yscript

Yeast cell factory for mRNA bioproduction

Programme
Horizon Europe & sub-programmes
Duration
42 months (April 2022 – September 2025)
Project funding
≈ €3 million
Project partners
8
Project website
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What the project is about

Messenger RNA (mRNA) vaccines have become a game-changer in the fight against COVID-19. Currently, in vitro transcription (IVT) is the only available technology for mRNA production; however, it relies on a complex supply chain and a costly purification process. Yscript’s groundbreaking nature lies in the generation of a specific mRNA bioproduction process in yeast, integrating innovative extraction and purification processes, representing a complete shift of paradigm compared to IVT production and a revolutionary new use of yeast. The project will significantly advance the current state of the art of mRNA manufacturing, which will foster citizens’ well-being and health while decreasing economic and social disparities associated with biopharmaceutical-based therapies.

Coordinator

Professor Chantal Pichon

CNRS

Email coordinator

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