FORCE REPAIR

Due to population lifestyle changes, i.e., obesity, diabetes and an ageing population, chronic wounds (CW) which fail to follow the typical healing process are a major medical and socioeconomic challenge. Current wound management is clearly insufficient and advanced therapies have failed to keep their promise of reliable skin regeneration. The aim of FORCE REPAIR is to develop a smart and multifunctional wound dressing providing a pro-regenerative environment and mechanical stability to treat CW. Thus, FORCE REPAIR will combine state-of-the-art technologies in a biological scaffold tailored to patients’ needs: (1) Antibacterial and bioadhesive bioink with antibiotics and anti-inflammatory loaded nanocapsules, (2) Elastin-like polypeptides promoting innervation and vascularisation, (3) Wharton Gel Complex preventing oxidative stress and boosting key extracellular matrix proteins.