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Predicting Long Term Toxic Effects Using Computer Models Based on Systems Characterization of Organotypic Cultures

NOTOX public symposium @ EUROTOX 2015

At the EUROTOX 2015 Congress – the 51st Congress of the European Societies of Toxicology, held on September 13-16 in Porto, Portugal – the NOTOX consortium proudly presented the exciting outcomes of its ambitious project. The Congress’ agenda covered a variety of topics highlighting the latest research results and trends in the field of toxicology.

The NOTOX symposium took place on September 14th during the EUROTOX 2015 Congress. The topics presented focused on the application of cellular systems that come closest to human in vivo situation and their transfer into applicable and easy-to-handle test systems. Prof. Magnus Ingelman-Sundberg (Karolinska Institutet) presented ‘Improved in vitro systems for prediction of hepatotoxicity’ while Fabrice Bertile (CRNS) discussed the newest research outcomes concerning ‘Toxicoproteomics applied to in vitro investigation of liver toxicity using HepaRG cells’. The topic of Model and in vitro based prediction of human hepatotoxicity waselaborated by Jan G. Hengstler (IfADo) and, finally, Lothar Terfloth (Insilico Biotechnology AG) provided participants with insights into the ‘Prediction of long term toxic effects by genome based network models’. Overall, the latest findings by the NOTOX consortium were well appreciated and the coordinators of the symposium, Elmar Heinzle and Fozia Noor, were pleased to welcome an audience of 200 attendees.

NOTOX is one of the building block projects of the European research initiative ‘Safety Evaluation Ultimately Replacing Animal Testing’ (SEURAT) funded by the EU-FP7 HEALTH programme and the European Cosmetics Association, Cosmetics Europe. The Eurice team is involved in NOTOX as management and dissemination partner and contributes to the successful implementation of the project goals.

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European Research and Project Office GmbH
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