Acronym
p-medicine
Full Title
From data sharing and integration via VPH models to personalized medicine
Programme
FP7–ICT Large-scale Integrating Project (IP)
Contract number
270089
Abstract
Medicine is undergoing a revolution transforming the nature of healthcare from reactive to preventive. This change is catalyzed by a new systems approach which focuses on integrated diagnosis, treatment and prevention of disease in individuals eventually leading to a personalized predictive treatment. p-medicine brings together international leaders in their fields to create an infrastructure that will facilitate this translation from current practice to personalized medicine. For this purpose p-medicine has formulated a coherent, integrated workplan for the design, development, integration of an open, modular framework of tools and services so that p-medicine can be adopted gradually, including efficient secure sharing and handling of large personalized data sets, enabling demanding Virtual Physiological Human (VPH) multiscale simulations (in silico oncology), building standards-compliant tools and models for VPH research, drawing on the VPH Toolkit and providing tools for large-scale, privacy-preserving data and literature mining, a key component of VPH research. It is understood that privacy, non-discrimination, and access policies are aligned to maximize protection of and benefit to patients. The p-medicine tools and technologies will be validated within the concrete setting of advanced clinical research. Pilot cancer trials have been selected based on clear research objectives, emphasising the need to integrate multilevel datasets, in the domains of Wilms tumour, breast cancer and leukaemia. To sustain a self-supporting infrastructure realistic use cases will be built demonstrating tangible results for clinicians.
Duration
48 months (February 1st, 2011 – January 31, 2015)
Project Funding
13,300,000.00 €
Coordinator
Saarland University,
Department of Paediatric Oncology and Haematology
Prof. Dr. Norbert Graf
Tel.: +49 6841 162 8397
Email
Partners
- European Research and Project Office GmbH, Germany (Corinna Hahn)
- Foundation for Research and Technology Hellas, Greece
Institute of Computer Science (Dr. Manolis Tsiknakis) - University College London, United Kingdom
Centre for Computational Science (Prof. Peter Coveney) - Molecular Haematology & Cancer Biology Unit (Prof. Kathy Prichard-Jones)
- Fraunhofer Institute for Biomedical Engineering, Germany (Stephan Kiefer)
- Fraunhofer Institute for Intelligent Analysis and Information Systems, Germany (Stefan Rüping)
- Gottfried Wilhelm Leibniz University Hannover, Germany
Institute of Legal Informatics (Prof. Dr. Nikolaus Forgó) - Custodix NV, Belgium (Brecht Claerhout)
- Philips Electronics Nederland B.V., the Netherlands
Philips Research Europe (Dr. Anca Bucur) - European Clinical Research Infrastructures Network (ECRIN) represented by Heinrich-Heine University Duesseldorf, Germany
Coordination Centre for Clinical Trials, Medical Faculty (Prof. Dr. Christian Ohmann) - Institute of Communication and Computer Systems, Greece
Microwave and Fiber Optics Laboratory – In Silico Oncology Group (Dr. Georgios Stamatakos) - Universidad Politécnica de Madrid, Spain
Biomedical Informatics Group, Artificial Intelligence Department (Prof. Victor Maojo, PhD) - Kiel University, Germany
Department of General Pediatrics (Prof. Dr. Martin Stanulla) - Istituto Europeo di Oncologia SRL, Italy
Department of Medicine (Prof. Aaron Goldhirsch, PhD) - ecancermedicalscience AG, Switzerland (Prof. Gordon McVie, PhD)
- University of Oxford, United Kingdom
Weatherall Institute of Molecular Medicine (Dr. Francesca Buffa) - Biovista, Greece (Dr. Andreas Persidis)
- Swiss Institute of Bioinformatics, Switzerland
Bioinformatics Core Facility (Dr. Mauro Delorenzi) - National University Corporation Hokkaido University, Japan
Meme Media Laboratory (Prof. Yuzuru Tanaka, PhD) - Poznan Supercomputing and Networking Center, Poland
Applications Department (Dr. Krzysztof Kurowski)
Contact at Eurice
Janine Hintz
Project Officer
Tel.: +49 681 9592 3364
Email